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Botanical Name :
Nardostachys grandiflora
Sanskrit Name: Jatamansi
English Name : Muskroot, Indian Spikenard,Jatamansi,Spikenard
Family : Valerianaceae
Part used: Rhizomes
Sanskrit Name: Jatamansi
English Name : Muskroot, Indian Spikenard,Jatamansi,Spikenard
Family : Valerianaceae
Part used: Rhizomes
Traditional uses:
The rhizome is used in ayurveda for the treatment of hysteria and other neurological disorders. It is very interesting to note that in conditions of insomnia and restlessness this drug was used by Sushruta to produce tranquility and sedation. it promotes the growth and blackness of hair. Infusion prepared from the fresh roots is employed in the treatment of spasmodic hysterical states, palpitations and tension headache. It is also said to be useful in menopausal disturbances.
The rhizome is used in ayurveda for the treatment of hysteria and other neurological disorders. It is very interesting to note that in conditions of insomnia and restlessness this drug was used by Sushruta to produce tranquility and sedation. it promotes the growth and blackness of hair. Infusion prepared from the fresh roots is employed in the treatment of spasmodic hysterical states, palpitations and tension headache. It is also said to be useful in menopausal disturbances.
Phytochemistry:
A volatile essential oil 0.5% resin, sugar, starch, bitter extractive matter and gum are obtained from the rhizome. Jatamansi oil contains a ketone, jatamansone which is the same as valeranone (in valerian). It also contains jatamansic acid. Jatamansone semi- carbazone is a sesquiterpenic ketone isolated from the rhizomes. It also has b-Gurjunene, a-patchoulene, hydroxy aristolenone.
A volatile essential oil 0.5% resin, sugar, starch, bitter extractive matter and gum are obtained from the rhizome. Jatamansi oil contains a ketone, jatamansone which is the same as valeranone (in valerian). It also contains jatamansic acid. Jatamansone semi- carbazone is a sesquiterpenic ketone isolated from the rhizomes. It also has b-Gurjunene, a-patchoulene, hydroxy aristolenone.
Pharmacology:
Jatamansone semicarbazone, a sesquiterpene ketone, was found to possess antioestrogenic activity. When given alone it is also manifested by its oestrogen-antagonising action on the uterus of mice at an oral dose of 50 mg/kg and 100 mg/kg. The volatile oil was found to be loss active than quinidine in several tests. Also it did not counteract digitalis induced ventricular arrhythmias. This drug has been experimentally shown to possess a tranquilizing and hypotensive activity in dogs and also induced hypotension in rats.
Jatamansone semicarbazone, a sesquiterpene ketone, was found to possess antioestrogenic activity. When given alone it is also manifested by its oestrogen-antagonising action on the uterus of mice at an oral dose of 50 mg/kg and 100 mg/kg. The volatile oil was found to be loss active than quinidine in several tests. Also it did not counteract digitalis induced ventricular arrhythmias. This drug has been experimentally shown to possess a tranquilizing and hypotensive activity in dogs and also induced hypotension in rats.
For further Inquiry Click here http://www.pioneerherbal.com/natural-extracts/jatamansi.html
The rhizome is used in ayurveda for
the treatment of hysteria and other neurological disorders. It
is very interesting to note that in conditions of insomnia and
restlessness this drug was used by Sushruta to produce
tranquility and sedation. it promotes the growth and blackness
of hair. Infusion prepared from the fresh roots is employed in
the treatment of spasmodic hysterical states, palpitations and
tension headache.
It is also said to be useful in menopausal
disturbances. Clinical trials were carried out with jatamansone
in essential hypertension. Jatamansone has been used in febrile
delirium and also in delirium tremens. In dysmenorrhoea, it is
used for pain relief and a smooth menstrual flow.
For further Inquiry Click here http://www.pioneerherbal.com/natural-extracts/jatamansi.html
LD(50) of Jatamansone was found to be 80.3 mg/kg while in the
case of quinidine it is 55 mg/kg. This shows that intravenous
toxicity in mice in the case of Jatamansone is less than that
with quinidine. Large doses of Jatamansone can cause vomiting
and diarrhoea.
Main Actions:
Anti - inflammatory, antipyretic, bactericidal, deodorant, fungicidal, laxative, sedative, tonic.
Anti - inflammatory, antipyretic, bactericidal, deodorant, fungicidal, laxative, sedative, tonic.
Main Uses:
Nervous agitation, hysteria, anxiety, painful menstruation,
pre-menstrual tension, sedative, yet also said to energize a
fatigued mind, irritible bowel syndrome
Marker constituent:
L-DOPA
L-DOPA
Main Uses:
Anti-parkinsonism, Aphrodisiac.
Anti-parkinsonism, Aphrodisiac.
General information:
The therapeutic benefits of Musk Root have been documented in various Ayurvedic texts. The herb is recommended for combating stress and insomnia. It is also known to enhance memory and treat mental instability. Cardiotonic properties have also been attributed to Musk Root.Therapeutic constituents:
The oil of Musk Root contains dnardostachone, valeranone and jatamansone as the major ketonic sesquiterpenes. These components give the herb its central tranquilizer and sedative properties.Key therapeutic benefits:
- As a tranquilizer, sedative and central nervous system depressant, Musk Root is used to treat stress and nervine disorders.
- It is also known to treat irregular heart palpitations and as a remedy for high blood pressure.
NARDOTACHYNS
JATAMANSI ( JATAMANSI )
|
|
| PRODUCT CODE: | NE/NJ/075 |
DESCRIPTION
|
LIGHT BROWN
COLOURED POWDER WITH CHARACTERISTIC ODOUR AND BITTER TASTE
.
|
IDENTIFICATION
|
(I) CHARACTERISTIC OF ODOUR
(II) PRESENCE OF JATANSINE BY T.L.C. |
SOLUBILITY
WATER 80% V/V ALCOHOL |
SPARINGLY SOLUBLE SPARINGLY SOLUBLE |
ASSAY
JATAMANSHI VOLATILE OIL |
1.0% MIN. 0.2% MIN. |
HERB EXT. RATIO
|
3:1
|
| NATURE OF EXTRACT | DRY EXTRACT. |
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*Disclaimer
"These statements have not been evaluated by the food and drug administration or any other regulatory body. These products are not intended to diagnose, treat, cure, or prevent any
disease.
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